Cotinine measurements in Belfast and Toulouse adults

their influence on blood micronutrient levels.

by Catherine B. Shevlin

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Published 1994 by The Author] in [S.l .
Written in English

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Edition Notes

Thesis (M. Sc. (Biomedical Sciences) - University of Ulster, 1994.

The Physical Object
Pagination	xvi, 121p., tables :
Number of Pages	121
ID Numbers
Open Library	OL21162767M

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This is a painless test used to detect an individual’s levels of exposure to tobacco and nicotine in the urine. The test samples can be obtained from the urine, blood, saliva and sometimes hair. The various levels of concentration of nicotine relative to the sample determine the seriousness of the. Cotinine diffuses easily from blood into saliva, and salivary cotinine and blood levels are highly correlated. (1) Cotinine in saliva has a longer half-life than nicotine (more than 10 hours), and the literature has documented it to be a specific and sensitive marker for determining exposure to tobacco and nicotine, allowing for primary and.

Cotinine (Serum) Test. A number of studies have shown the effects of passive smoke on the respiratory, circulatory, and immune systems of children and adults. In order to be able to correlate the health status of individuals specifically with exposure to tobacco smoke, it has become important to have an assay capable of detecting nanogram. The DRI Cotinine Assay is a homogeneous enzyme immunoassay based on competition between cotinine labeled with the glucosephosphate dehydrogenase enzyme and free cotinine. We applied a urine cotinine cut-off point of ng/mL in reference to a previous study, in which nonsmoker urine cotinine levels did not exceed ng/mL [ 17 ].Cited by: 3. Chemical measurements using different analytical approaches showed differences in limits of detection and other discrepancies that prevent direction comparison. Non‐chemical stressors such as economic and social impacts on the subjects mirrored the measurement .

Recently developed semiquantitative urine cotinine measurement techniques (i.e., urine immunoassay test strips, or ITS) address these disadvantages, though the value of ITS as a means of identifying abstaining smokers has not been evaluated. The present study examined ITS as a measure of smoking status in temporarily abstaining by: Cotinine can be detected in urine up to 3 days after nicotine use, using a detection cutoff of ng/mL. Because of its longer window of detection, cotinine is the best biomarker of smoking. Preoperative testing can be performed with a rapid point of care test for urine cotinine. Cotinine is a chemical produced when the body is exposed to nicotine found in tobacco products. Any type of product containing nicotine can cause the body to produce Cotinine and can be present even if a person isn’t a fact second hand smoke can cause non smokers to have as much Cotinine in their blood as an occasional smoker.